What are the causes of prostatitis?

With the increase in social pressure, male friends to bear the enormous psychological pressure, it is for this reason, the health of male friends gradually problems, some male diseases also become male friends difficult to get rid of the problem, which has become the pain of male friends , Then, what causes the prostate? Here we look at the introduction of experts it
        Type Ⅰ prostatitis
Pathogen infection is the main risk factor. Due to the body resistance is low, more virulent bacteria or other pathogens infected with the prostate and rapid growth and reproduction caused by a large number of blood infection, transurethral retrograde infection. Pathogens are mainly Escherichia coli, followed by Staphylococcus aureus, Klebsiella pneumoniae, Proteus, Pseudomonas, etc., the vast majority of single pathogen infection.

Type Ⅱ prostatitis
Pathogenic factors are mainly pathogens, but the body resistance is strong and / and the pathogen virulence is weak, mainly retrograde infection, pathogens mainly Staphylococcus, followed by Escherichia coli, Corynebacterium and Enterococcus And so on. Prostate stones and urinary reflux may be an important cause of persistent pathogens and recurrence of infection.
Type Ⅲ prostatitis
The pathogenesis is unexplained, and the etiology is complex and there is widespread controversy: it may be caused by a starting factor, or it may be a multifactor at first, one or several of which plays a key role and affects each other; Difficult to identify the different diseases, but with the same or similar clinical manifestations; even these diseases have been cured, and it caused damage and pathological changes still continue to work independently. Most scholars believe that the main cause may be pathogens infection, inflammation and abnormal pelvic floor neuromuscular activity and immune abnormalities and other common results.
1. Pathogen infection in this type of patients Although the routine bacterial examination failed to isolate the pathogens, but may still with some special pathogens: such as anaerobic bacteria, L-type bacteria, nano-bacteria, or Chlamydia trachomatis, mycoplasma and other infections. Studies have shown that the type of local prokaryotic DNA detection rate can be as high as 77%; some of the clinical chronic inflammation, recurrent or aggravated "aseptic" prostatitis may be related to these pathogens. Other pathogens such as parasites, fungi, viruses, trichomoniasis, Mycobacterium tuberculosis, etc. may also be the type of important pathogenic factors, but the lack of reliable evidence, there is no consensus.
2. urinary dysfunction Some factors cause excessive contraction of the urethral sphincter, leading to bladder outlet obstruction and residual urine formation, resulting in urine into the prostate, not only can pathogen into the prostate, but also directly stimulate the prostate, induced aseptic "chemical Sex prostatitis ", causing abnormal urination and pelvic pain.
Many patients with prostatitis there are a variety of urodynamic changes, such as: reduced urinary flow, functional urinary tract obstruction, detrusor - urethral sphincter disorders and so on. These functional abnormalities may be only a clinical phenomenon, its nature may be related to the potential of various pathogenic factors.
3. Psycho-psychological factors show that: more than half of patients with prolonged unhealed prostatitis there are significant mental and psychological changes in personality characteristics. Such as: anxiety, depression, hypochondria, hysteria, and even suicidal tendencies. These changes in mental and psychological factors can cause autonomic dysfunction, resulting in posterior urethral neuromuscular dysfunction, leading to pelvic regional pain and voiding dysfunction; or cause hypothalamus - pituitary - gonadal axis changes affect sexual function, further aggravating symptoms , To eliminate mental stress can ease the symptoms or recovery. But it is not clear whether the psychological change is the direct cause, or secondary performance.
4. Neuroendocrine factors Prostate pain patients are prone to heart rate and blood pressure fluctuations, indicating that may be related to autonomic nerve response. The pain has the characteristics of internal organs pain, prostate, urethral local pathological stimulation, through the prostate nerve afferent nerve trigger spinal cord reflex, activation of the waist, sacral spinal astrocytes, nerve impulses through the reproductive femoral nerve and iliac groin nerve Impulsive, sympathetic nerve endings release norepinephrine, prostaglandins, calcitonin gene-related peptide, substance P, causing bladder and urethral dysfunction, and lead to perineum, pelvic floor muscle abnormalities, in the corresponding areas outside the prostate continue The pain and the pain involved.
5. Immunoreaction abnormalities Recent studies have shown that immune factors in the development and progression of type III prostatitis play a very important role in the patient's prostatic fluid and / or seminal and / or tissue and / or blood can be a IL-2, IL-6, IL-8, IL-10, TNF-α and MCP-1, and IL-10 levels were positively correlated with pain symptoms in patients with type III prostatitis , The application of immunosuppressive therapy has a certain effect.
6. Oxidative stress theory Under normal circumstances, the body of oxygen free radicals generated, use, clear in a dynamic equilibrium state. Prostatitis patients with oxygen free radicals produced too much and / or free radical scavenging system relative reduction, so that the body's ability to respond to antioxidant stress, oxidative stress products and / or by-products increased, may also be One of the pathogenesis.
7. Pelvic disease-related factors Some patients with prostatitis often accompanied by peripheral venous plexus plexus dilatation, hemorrhoids, varicocele, etc., suggesting that some patients with chronic prostatitis symptoms may be associated with pelvic vein congestion, blood stagnation, which may also Is one of the reasons for the long-standing cause.
Type IV prostatitis
Due to no clinical symptoms, often due to other related diseases were found, so the lack of pathogenesis of the relevant research data, may be part of the type Ⅲ prostatitis and pathogenesis of the same.
Prostatitis factors
Prostate inflammation of the important causes include: smoking, drinking, addicted to spicy food, inappropriate activities, sedentary caused by long-term congestion of the prostate and pelvic floor muscles long-term chronic extrusion, cold, fatigue and other physical resistance decline or specific physical and so on.
        Through the above experts on the introduction of prostate disease, I believe we must have a profound understanding. Hope that male friends must pay more attention to the prevention of prostatitis, less smoking, less alcohol, avoid spicy, greasy food, I believe that as long as you pay attention, it will be successful away from prostatitis. Finally, I wish you all healthy!